Zinc and iron relationship

Are Iron & Zinc Important Minerals? | Healthy Eating | SF Gate

zinc and iron relationship

For each 1 mg/day increase in dietary iron intake, zinc intake however there are no data on zinc status to explore this relationship in. Low consumption of foods rich in bioavailable iron (Fe) and zinc (Zn) factors in the relationship between iron deficiency and brain function. Iron and zinc are important minerals needed for good health. Iron is required for oxygen to travel to the tissues and organs, while zinc prevents illness by.

In contrast, mild Zn deficiency had no effect on whole-brain catecholamines Halas et al. A special class of glutaminergic neurons has Zn-containing vesicles in its axon terminals Frederickson and Moncrieff Vesicle Zn released during neurotransmission modulates postsynaptic N-methyl-D-aspartate receptors for glutamate Westbrook and Mayerincluding calcium-channels Browning and O'Dell In vitro findings indicate that oxidation of metallothionein by oxidized glutathione or analogous selenium compounds releases Zn to specific ligands.

zinc and iron relationship

Glutathione and ATP facilitate this process Jacob et al. Zn-ATP is necessary for synthesis of pyridoxalphosphate Churchich et al. Acute Zn deficiency impairs electrophysiology and behavior of rats HesseHesse et al.

Zn deficiency during early brain development causes malformations Hurley and Swenerton Zn deficiency during later brain development impairs neuronal growth and synaptogenesis Dvergstenand causes behavioral sequellae Golub et al. Relationships between Zn-nutriture and brain function of humans have been reported.

In Egyptian women, consumption of foods derived from animals rich in Zn during pregnancy was associated with their infants having higher attention scores on the Brazelton Neonatal Development Assessment Scale Kirksey et al.

At 6 mo of age, motor performance on the Bayley Scales of Infant Development was inversely related to maternal intakes of low bioavailable Zn from plants, phytate and fiber Kirksey et al.

Low hair Zn concentration, an indicator of low Zn status, was associated with poor reading performance and decreased EEG coherence in the frontal lobe Thatcher et al. Two wk double-blind, randomized controlled trials found improved neuropsychologic function in Chinese Sandstead et al.

A postmortem study of 12 elderly women found a negative association between plasma Zn 1 y before death and the number of senile and diffuse plaques in their brains Tully et al. There were no significant differences across the 4 groups at baseline or endline. Zinc deficiency was observed in Discussion In the present study, women randomly assigned to receive daily or weekly Fe-FA supplements with or without zinc.

zinc and iron relationship

Neither daily nor weekly supplementation changed Hb concentrations, and the addition of zinc did not influence Hb concentrations. However, Hb concentrations improved significantly in women who were anemic at baseline by an average of For serum ferritin, significant between- and within-group changes were noted.

After supplementation, daily groups showed a much greater increase in serum ferritin concentrations than the weekly groups, suggesting that daily iron supplementation was more efficacious than weekly supplementation in improving serum ferritin concentrations. The addition of zinc to supplements containing iron had no influence on serum ferritin.

Although daily or intermittent iron supplementation, with and without zinc, significantly increased serum ferritin concentration, it did not reduce the percentage of anemic women.

Iron and zinc interactions in humans.

One possible explanation is that iron deficiency may be only one of several causes of anemia. Mean Hb concentrations improved significantly in women who were anemic at baseline by Our findings showed that adding zinc to supplements containing iron did not influence iron status but also did not improve zinc status in WRA.

zinc and iron relationship

Therefore, adding zinc to IFA supplements may not be an optimal way to improve zinc status in women. The addition of zinc to IFA may have other benefits for women, but there is limited information.

Iron and zinc interactions in humans.

Findings from this study suggested that adding zinc to IFA tablets did not affect the duration of pregnancy, size at birth, or developmental outcomes in Peruvian children when assessed at 4.

A study in Ghana found no difference in the mean weight of newborns of women receiving a combined supplement of zinc and iron compared to those of women receiving iron alone [ 24 ]. In a trial in Nepal [ 25 ], pregnant women were allocated at random to five regimens: Also, there was no difference in the proportion of preterm births between these two groups [ 25 ].

zinc and iron relationship

Finally, fetal loss and infant mortality did not differ between the groups who received IFA only and IFA with zinc [ 2627 ]. Thus, adding zinc to IFA supplements for women needs to be reconsidered since it appears to not benefit biochemical indicators or functional indicators. More studies that assess the impact of combined iron and zinc on functional status are needed to provide scientific evidence for public health policy.

Causes If you have had intestinal surgery or a gastrointestinal disorder, you may develop iron and zinc deficiencies because your body cannot absorb these nutrients.

Are Iron & Zinc Important Minerals?

Because meat provides a rich source of iron and zinc, vegetarians may develop iron and zinc deficiencies. The National Heart Lung and Blood Institute says low iron levels can be caused by blood loss due to severe injuries, internal bleeding or surgery.

Women with heavy and frequent menstrual periods are likely to develop iron deficiency. Children and pregnant women may also develop low iron levels because of the rapid body changes and high iron demands. People with sickle cell disease and alcoholics are likely to develop zinc deficiency. Symptoms Iron deficiency can lead to iron deficiency anemia, which may cause fatigue and weakness because the body does not have enough red blood cells.

Other symptoms are loss of appetite, rapid heartbeat, shortness of breath and dizziness. In infants and children, iron deficiency can lead to impaired growth and behavioral problems.

zinc and iron relationship